Structural and Biochemical Characterization of Human PR70 in Isolation and in Complex with the Scaff...
Structural and Biochemical Characterization of Human PR70 in Isolation and in Complex with the Scaffolding Subunit of Protein Phosphatase 2A
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Protein Phosphatase 2A (PP2A) is a major Ser/Thr phosphatase involved in the regulation of various cellular processes. PP2A assembles into diverse trimeric holoenzymes, which consist of a scaffolding (A) subunit, a catalytic (C) subunit and various regulatory (B) subunits. Here we report a 2.0 Å crystal structure of the free B''/PR70 subunit and a...
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Structural and Biochemical Characterization of Human PR70 in Isolation and in Complex with the Scaffolding Subunit of Protein Phosphatase 2A
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TN_cdi_plos_journals_1544135952
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1544135952
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0101846