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Tocilizumab, a Proposed Therapy for the Cachexia of Interleukin6-Expressing Lung Cancer

Tocilizumab, a Proposed Therapy for the Cachexia of Interleukin6-Expressing Lung Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1544377468

Tocilizumab, a Proposed Therapy for the Cachexia of Interleukin6-Expressing Lung Cancer

About this item

Full title

Tocilizumab, a Proposed Therapy for the Cachexia of Interleukin6-Expressing Lung Cancer

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-07, Vol.9 (7), p.e102436

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

We previously reported the role of IL-6 in a murine model of cancer cachexia and currently documented a patient in whom tocilizumab, anti-IL-6 receptor antibody, dramatically improved cachexia induced by IL-6 over-expressing lung cancer. Despite this potential to alleviate cancer cachexia, tocilizumab has not been approved for this clinical use. Th...

Alternative Titles

Full title

Tocilizumab, a Proposed Therapy for the Cachexia of Interleukin6-Expressing Lung Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1544377468

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1544377468

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0102436

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