BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells
BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The hypermetabolic nature of cancer cells and their increased reliance on "aerobic glycolysis", as originally described by Otto Warburg and colleagues, are considered metabolic hallmarks of cancer cells. BRCA1 is a major tumor suppressor in breast cancer and it was implicated in numerous pathways resulting in anticarcinogenic functions. The objecti...
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BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells
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TN_cdi_plos_journals_1544377764
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1544377764
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0102438