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BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1544377764

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

About this item

Full title

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-07, Vol.9 (7), p.e102438-e102438

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The hypermetabolic nature of cancer cells and their increased reliance on "aerobic glycolysis", as originally described by Otto Warburg and colleagues, are considered metabolic hallmarks of cancer cells. BRCA1 is a major tumor suppressor in breast cancer and it was implicated in numerous pathways resulting in anticarcinogenic functions. The objecti...

Alternative Titles

Full title

BRCA1 Induces Major Energetic Metabolism Reprogramming in Breast Cancer Cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1544377764

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1544377764

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0102438

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