TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy
TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Activating mutations in the Transient Receptor Potential channel C6 (TRPC6) cause autosomal dominant focal segmental glomerular sclerosis (FSGS). TRPC6 expression is upregulated in renal biopsies of patients with idiopathic membranous glomerulopathy (iMN) and animal models thereof. In iMN, disease progression is characterized by glomerulosclerosis....
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Full title
TRPC6 single nucleotide polymorphisms and progression of idiopathic membranous nephropathy
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TN_cdi_plos_journals_1545002634
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1545002634
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0102065
