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Effects of Treatment with Suppressive Combination Antiretroviral Drug Therapy and the Histone Deacet...

Effects of Treatment with Suppressive Combination Antiretroviral Drug Therapy and the Histone Deacet...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1545822124

Effects of Treatment with Suppressive Combination Antiretroviral Drug Therapy and the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid; (SAHA) on SIV-Infected Chinese Rhesus Macaques

About this item

Full title

Effects of Treatment with Suppressive Combination Antiretroviral Drug Therapy and the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid; (SAHA) on SIV-Infected Chinese Rhesus Macaques

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-07, Vol.9 (7), p.e102795

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Viral reservoirs-persistent residual virus despite combination antiretroviral therapy (cART)-remain an obstacle to cure of HIV-1 infection. Difficulty studying reservoirs in patients underscores the need for animal models that mimics HIV infected humans on cART. We studied SIV-infected Chinese-origin rhesus macaques (Ch-RM) treated with intensive c...

Alternative Titles

Full title

Effects of Treatment with Suppressive Combination Antiretroviral Drug Therapy and the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid; (SAHA) on SIV-Infected Chinese Rhesus Macaques

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1545822124

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1545822124

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0102795

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