Biogenesis of Influenza A Virus Hemagglutinin Cross-Protective Stem Epitopes
Biogenesis of Influenza A Virus Hemagglutinin Cross-Protective Stem Epitopes
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Antigenic variation in the globular domain of influenza A virus (IAV) hemagglutinin (HA) precludes effective immunity to this major human pathogen. Although the HA stem is highly conserved between influenza virus strains, HA stem-reactive antibodies (StRAbs) were long considered biologically inert. It is now clear, however, that StRAbs reduce viral...
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Biogenesis of Influenza A Virus Hemagglutinin Cross-Protective Stem Epitopes
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TN_cdi_plos_journals_1547573051
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1547573051
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ISSN
1553-7374,1553-7366
E-ISSN
1553-7374
DOI
10.1371/journal.ppat.1004204