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Biogenesis of Influenza A Virus Hemagglutinin Cross-Protective Stem Epitopes

Biogenesis of Influenza A Virus Hemagglutinin Cross-Protective Stem Epitopes

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1547573051

Biogenesis of Influenza A Virus Hemagglutinin Cross-Protective Stem Epitopes

About this item

Full title

Biogenesis of Influenza A Virus Hemagglutinin Cross-Protective Stem Epitopes

Publisher

United States: Public Library of Science

Journal title

PLoS pathogens, 2014-06, Vol.10 (6), p.e1004204-e1004204

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Antigenic variation in the globular domain of influenza A virus (IAV) hemagglutinin (HA) precludes effective immunity to this major human pathogen. Although the HA stem is highly conserved between influenza virus strains, HA stem-reactive antibodies (StRAbs) were long considered biologically inert. It is now clear, however, that StRAbs reduce viral...

Alternative Titles

Full title

Biogenesis of Influenza A Virus Hemagglutinin Cross-Protective Stem Epitopes

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1547573051

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1547573051

Other Identifiers

ISSN

1553-7374,1553-7366

E-ISSN

1553-7374

DOI

10.1371/journal.ppat.1004204

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