PINK1-Mediated Phosphorylation of Parkin Boosts Parkin Activity in Drosophila
PINK1-Mediated Phosphorylation of Parkin Boosts Parkin Activity in Drosophila
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Two genes linked to early onset Parkinson's disease, PINK1 and Parkin, encode a protein kinase and a ubiquitin-ligase, respectively. Both enzymes have been suggested to support mitochondrial quality control. We have reported that Parkin is phosphorylated at Ser65 within the ubiquitin-like domain by PINK1 in mammalian cultured cells. However, it rem...
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PINK1-Mediated Phosphorylation of Parkin Boosts Parkin Activity in Drosophila
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TN_cdi_plos_journals_1547593249
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1547593249
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1553-7404,1553-7390
E-ISSN
1553-7404
DOI
10.1371/journal.pgen.1004391
