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Cloning and Characterization of a Norbelladine 4′-O-Methyltransferase Involved in the Biosynthesis o...

Cloning and Characterization of a Norbelladine 4′-O-Methyltransferase Involved in the Biosynthesis o...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1548413573

Cloning and Characterization of a Norbelladine 4′-O-Methyltransferase Involved in the Biosynthesis of the Alzheimer’s Drug Galanthamine in Narcissus sp. aff. pseudonarcissus

About this item

Full title

Cloning and Characterization of a Norbelladine 4′-O-Methyltransferase Involved in the Biosynthesis of the Alzheimer’s Drug Galanthamine in Narcissus sp. aff. pseudonarcissus

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-07, Vol.9 (7), p.e103223-e103223

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Galanthamine is an Amaryllidaceae alkaloid used to treat the symptoms of Alzheimer's disease. This compound is primarily isolated from daffodil (Narcissus spp.), snowdrop (Galanthus spp.), and summer snowflake (Leucojum aestivum). Despite its importance as a medicine, no genes involved in the biosynthetic pathway of galanthamine have been identifie...

Alternative Titles

Full title

Cloning and Characterization of a Norbelladine 4′-O-Methyltransferase Involved in the Biosynthesis of the Alzheimer’s Drug Galanthamine in Narcissus sp. aff. pseudonarcissus

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1548413573

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1548413573

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0103223

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