Facile Enzymatic Synthesis of Base J-Containing Oligodeoxyribonucleotides and an Analysis of the Imp...
Facile Enzymatic Synthesis of Base J-Containing Oligodeoxyribonucleotides and an Analysis of the Impact of Base J on DNA Replication in Cells
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United States: Public Library of Science
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English
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United States: Public Library of Science
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We reported here the use of T4 bacteriophage β-glucosyltransferase (T4 β-GT) for the facile synthesis of base J-containing oligodeoxyribonucleotides (ODNs). We found that the enzyme could catalyze the glucosylation of 5-hydroxymethyl-2-deoxyuridine (5hmU) in both single- and double-stranded ODNs, though the latter reaction occurred only when 5hmU w...
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Full title
Facile Enzymatic Synthesis of Base J-Containing Oligodeoxyribonucleotides and an Analysis of the Impact of Base J on DNA Replication in Cells
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TN_cdi_plos_journals_1548413655
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1548413655
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1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0103335
