Compact Conformations of Human Protein Disulfide Isomerase
Compact Conformations of Human Protein Disulfide Isomerase
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Author / Creator
Yang, Shang , Wang, Xi , Cui, Lei , Ding, Xiang , Niu, Lili , Yang, Fuquan , Wang, Chao , Wang, Chih-chen and Lou, Jizhong
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Protein disulfide isomerase (PDI) composed of four thioredoxin-like domains a, b, b', and a', is a key enzyme catalyzing oxidative protein folding in the endoplasmic reticulum. Large scale molecular dynamics simulations starting from the crystal structures of human PDI (hPDI) in the oxidized and reduced states were performed. The results indicate t...
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Full title
Compact Conformations of Human Protein Disulfide Isomerase
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Record Identifier
TN_cdi_plos_journals_1550514086
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1550514086
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0103472
