Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's diseas...
Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Neprilysin is a transmembrane zinc metallopeptidase that degrades a wide range of peptide substrates. It has received attention as a potential therapy for Alzheimer's disease due to its ability to degrade the peptide amyloid beta. However, its broad range of peptide substrates has the potential to limit its therapeutic use due to degradation of add...
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Full title
Engineering neprilysin activity and specificity to create a novel therapeutic for Alzheimer's disease
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TN_cdi_plos_journals_1551148547
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1551148547
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0104001
