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[6]-Gingerol Induces Caspase-Dependent Apoptosis and Prevents PMA-Induced Proliferation in Colon Can...

[6]-Gingerol Induces Caspase-Dependent Apoptosis and Prevents PMA-Induced Proliferation in Colon Can...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1556306975

[6]-Gingerol Induces Caspase-Dependent Apoptosis and Prevents PMA-Induced Proliferation in Colon Cancer Cells by Inhibiting MAPK/AP-1 Signaling

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Full title

[6]-Gingerol Induces Caspase-Dependent Apoptosis and Prevents PMA-Induced Proliferation in Colon Cancer Cells by Inhibiting MAPK/AP-1 Signaling

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-08, Vol.9 (8), p.e104401

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

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Scope and Contents

Contents

We report mechanism-based evidence for the anticancer and chemopreventive efficacy of [6]-gingerol, the major active principle of the medicinal plant, Ginger (Zingiber officinale), in colon cancer cells. The compound was evaluated in two human colon cancer cell lines for its cytotoxic effect and the most sensitive cell line, SW-480, was selected fo...

Alternative Titles

Full title

[6]-Gingerol Induces Caspase-Dependent Apoptosis and Prevents PMA-Induced Proliferation in Colon Cancer Cells by Inhibiting MAPK/AP-1 Signaling

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Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1556306975

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1556306975

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0104401

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