Tetramethoxychalcone, a Chalcone Derivative, Suppresses Proliferation, Blocks Cell Cycle Progression...
Tetramethoxychalcone, a Chalcone Derivative, Suppresses Proliferation, Blocks Cell Cycle Progression, and Induces Apoptosis of Human Ovarian Cancer Cells
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Author / Creator
Qi, Zihao , Liu, Mingming , Liu, Yang , Zhang, Meiqin and Yang, Gong
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
In the present study, we investigated the in vitro antitumor functions of a synthetic chalcone derivative 4,3',4',5'- tetramethoxychalcone (TMOC) in ovarian cancer cells. We found that TMOC inhibited the proliferation and colony formation of cisplatin sensitive cell line A2780 and resistant cell line A2780/CDDP, as well as ovarian cancer cell line...
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Full title
Tetramethoxychalcone, a Chalcone Derivative, Suppresses Proliferation, Blocks Cell Cycle Progression, and Induces Apoptosis of Human Ovarian Cancer Cells
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TN_cdi_plos_journals_1559041475
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1559041475
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0106206
