Development of a Physiologically Based Model to Describe the Pharmacokinetics of Methylphenidate in...
Development of a Physiologically Based Model to Describe the Pharmacokinetics of Methylphenidate in Juvenile and Adult Humans and Nonhuman Primates
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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The widespread usage of methylphenidate (MPH) in the pediatric population has received considerable attention due to its potential effect on child development. For the first time a physiologically based pharmacokinetic (PBPK) model has been developed in juvenile and adult humans and nonhuman primates to quantitatively evaluate species- and age-depe...
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Development of a Physiologically Based Model to Describe the Pharmacokinetics of Methylphenidate in Juvenile and Adult Humans and Nonhuman Primates
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TN_cdi_plos_journals_1559783805
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1559783805
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0106101
