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Inhibition of tyrosine kinase receptor Tie2 reverts HCV-induced hepatic stellate cell activation

Inhibition of tyrosine kinase receptor Tie2 reverts HCV-induced hepatic stellate cell activation

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1610133297

Inhibition of tyrosine kinase receptor Tie2 reverts HCV-induced hepatic stellate cell activation

About this item

Full title

Inhibition of tyrosine kinase receptor Tie2 reverts HCV-induced hepatic stellate cell activation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-10, Vol.9 (10), p.e106958-e106958

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Hepatitis C virus (HCV) infection is a major cause of chronic liver disease (CLD) and is frequently linked to intrahepatic microvascular disorders. Activation of hepatic stellate cells (HSC) is a central event in liver damage, due to their contribution to hepatic renewal and to the development of fibrosis and hepatocarcinoma. During the progression...

Alternative Titles

Full title

Inhibition of tyrosine kinase receptor Tie2 reverts HCV-induced hepatic stellate cell activation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1610133297

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1610133297

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0106958

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