HDAC1 controls CD8+ T cell homeostasis and antiviral response
HDAC1 controls CD8+ T cell homeostasis and antiviral response
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Reversible lysine acetylation plays an important role in the regulation of T cell responses. HDAC1 has been shown to control peripheral T helper cells, however the role of HDAC1 in CD8+ T cell function remains elusive. By using conditional gene targeting approaches, we show that LckCre-mediated deletion of HDAC1 led to reduced numbers of thymocytes...
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Full title
HDAC1 controls CD8+ T cell homeostasis and antiviral response
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TN_cdi_plos_journals_1615769871
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1615769871
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0110576
