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Impact of temporal variation on design and analysis of mouse knockout phenotyping studies

Impact of temporal variation on design and analysis of mouse knockout phenotyping studies

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1616171574

Impact of temporal variation on design and analysis of mouse knockout phenotyping studies

About this item

Full title

Impact of temporal variation on design and analysis of mouse knockout phenotyping studies

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-10, Vol.9 (10), p.e111239-e111239

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

A significant challenge facing high-throughput phenotyping of in-vivo knockout mice is ensuring phenotype calls are robust and reliable. Central to this problem is selecting an appropriate statistical analysis that models both the experimental design (the workflow and the way control mice are selected for comparison with knockout animals) and the s...

Alternative Titles

Full title

Impact of temporal variation on design and analysis of mouse knockout phenotyping studies

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1616171574

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1616171574

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0111239

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