Oxidative stress induces persistent telomeric DNA damage responsible for nuclear morphology change i...
Oxidative stress induces persistent telomeric DNA damage responsible for nuclear morphology change in mammalian cells
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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One main function of telomeres is to maintain chromosome and genome stability. The rate of telomere shortening can be accelerated significantly by chemical and physical environmental agents. Reactive oxygen species are a source of oxidative stress and can produce modified bases (mainly 8-oxoG) and single strand breaks anywhere in the genome. The hi...
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Full title
Oxidative stress induces persistent telomeric DNA damage responsible for nuclear morphology change in mammalian cells
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TN_cdi_plos_journals_1618152616
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1618152616
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0110963
