An Interaction of Renin-Angiotensin and Kallikrein-Kinin Systems Contributes to Vascular Hypertrophy...
An Interaction of Renin-Angiotensin and Kallikrein-Kinin Systems Contributes to Vascular Hypertrophy in Angiotensin II-Induced Hypertension: In Vivo and In Vitro Studies
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Author / Creator
Ceravolo, Graziela S. , Montezano, Augusto C. , Jordão, Maria T. , Akamine, Eliana H. , Costa, Tiago J. , Takano, Ana P. , Fernandes, Denise C. , Barreto-Chaves, Maria L. , Laurindo, Francisco R. , Tostes, Rita C. , Fortes, Zuleica B. , Chopard, Renato P. , Touyz, Rhian M. and Carvalho, Maria Helena C.
Publisher
United States: Public Library of Science
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English
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Publisher
United States: Public Library of Science
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Contents
The kallikrein-kinin and renin-angiotensin systems interact at multiple levels. In the present study, we tested the hypothesis that the B1 kinin receptor (B1R) contributes to vascular hypertrophy in angiotensin II (ANG II)-induced hypertension, through a mechanism involving reactive oxygen species (ROS) generation and extracellular signal-regulated...
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Full title
An Interaction of Renin-Angiotensin and Kallikrein-Kinin Systems Contributes to Vascular Hypertrophy in Angiotensin II-Induced Hypertension: In Vivo and In Vitro Studies
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TN_cdi_plos_journals_1620165331
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1620165331
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0111117
