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Regulation of the Orphan Nuclear Receptor Nr2f2 by the DFNA15 Deafness Gene Pou4f3

Regulation of the Orphan Nuclear Receptor Nr2f2 by the DFNA15 Deafness Gene Pou4f3

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1620594932

Regulation of the Orphan Nuclear Receptor Nr2f2 by the DFNA15 Deafness Gene Pou4f3

About this item

Full title

Regulation of the Orphan Nuclear Receptor Nr2f2 by the DFNA15 Deafness Gene Pou4f3

Publisher

United States: Public Library of Science

Journal title

PloS one, 2014-11, Vol.9 (11), p.e112247-e112247

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Hair cells are the mechanotransducing cells of the inner ear that are essential for hearing and balance. POU4F3--a POU-domain transcription factor selectively expressed by these cells--has been shown to be essential for hair cell differentiation and survival in mice and its mutation in humans underlies late-onset progressive hearing loss (DFNA15)....

Alternative Titles

Full title

Regulation of the Orphan Nuclear Receptor Nr2f2 by the DFNA15 Deafness Gene Pou4f3

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1620594932

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1620594932

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0112247

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