Regulation of the Orphan Nuclear Receptor Nr2f2 by the DFNA15 Deafness Gene Pou4f3
Regulation of the Orphan Nuclear Receptor Nr2f2 by the DFNA15 Deafness Gene Pou4f3
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Hair cells are the mechanotransducing cells of the inner ear that are essential for hearing and balance. POU4F3--a POU-domain transcription factor selectively expressed by these cells--has been shown to be essential for hair cell differentiation and survival in mice and its mutation in humans underlies late-onset progressive hearing loss (DFNA15)....
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Regulation of the Orphan Nuclear Receptor Nr2f2 by the DFNA15 Deafness Gene Pou4f3
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TN_cdi_plos_journals_1620594932
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1620594932
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0112247