Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels
Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
CALHM1 is a plasma membrane voltage-gated Ca2+-permeable ion channel that controls amyloid-β (Aβ) metabolism and is potentially involved in the onset of Alzheimer's disease (AD). Recently, Rubio-Moscardo et al. (PLoS One (2013) 8: e74203) reported the identification of two CALHM1 variants, G330D and R154H, in early-onset AD (EOAD) patients. The aut...
Alternative Titles
Full title
Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1622597674
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1622597674
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0112484
