Simplexide Induces CD1d-Dependent Cytokine and Chemokine Production from Human Monocytes
Simplexide Induces CD1d-Dependent Cytokine and Chemokine Production from Human Monocytes
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Monocytes are major effector cells of innate immunity and recognize several endogenous and exogenous molecules due to the expression of wide spectrum of receptors. Among them, the MHC class I-like molecule CD1d interacts with glycolipids and presents them to iNKT cells, mediating their activation. Simplexide belongs to a novel class of glycolipids...
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Full title
Simplexide Induces CD1d-Dependent Cytokine and Chemokine Production from Human Monocytes
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TN_cdi_plos_journals_1623314890
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1623314890
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0111326
