Epidermal growth factor receptor inhibition with erlotinib partially prevents cisplatin-induced neph...
Epidermal growth factor receptor inhibition with erlotinib partially prevents cisplatin-induced nephrotoxicity in rats
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Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
The effects of blocking the epidermal growth factor receptor (EGFR) in acute kidney injury (AKI) are controversial. Here we investigated the renoprotective effect of erlotinib, a selective tyrosine kinase inhibitor that can block EGFR activity, on cisplatin (CP)-induced AKI. Groups of animals were given either erlotinib or vehicle from one day befo...
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Full title
Epidermal growth factor receptor inhibition with erlotinib partially prevents cisplatin-induced nephrotoxicity in rats
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TN_cdi_plos_journals_1623315034
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1623315034
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0111728
