Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functio...
Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene
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Author / Creator
Lai, Courteney K , Moon, Yeonsook , Kuchenbauer, Florian , Starzcynowski, Daniel T , Argiropoulos, Bob , Yung, Eric , Beer, Philip , Schwarzer, Adrian , Sharma, Amit , Park, Gyeongsin , Leung, Malina , Lin, Grace , Vollett, Sarah , Fung, Stephen , Eaves, Connie J , Karsan, Aly , Weng, Andrew P , Humphries, R Keith and Heuser, Michael
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Extensive molecular profiling of leukemias and preleukemic diseases has revealed that distinct clinical entities, like acute myeloid (AML) and T-lymphoblastic leukemia (T-ALL), share similar pathogenetic mutations. It is not well understood how the cell of origin, accompanying mutations, extracellular signals or structural differences in a mutated...
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Cell fate decisions in malignant hematopoiesis: leukemia phenotype is determined by distinct functional domains of the MN1 oncogene
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TN_cdi_plos_journals_1625576678
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1625576678
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0112671
