Forward Genetic Screening for Regulators Involved in Cholesterol Synthesis Using Validation-Based In...
Forward Genetic Screening for Regulators Involved in Cholesterol Synthesis Using Validation-Based Insertional Mutagenesis
About this item
Full title
Author / Creator
Jiang, Wei , Tang, Jing-Jie , Miao, Hong-Hua , Qu, Yu-Xiu , Qin, Jie , Xu, Jie , Yang, Jinbo , Li, Bo-Liang and Song, Bao-Liang
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
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Scope and Contents
Contents
Somatic cell genetics is a powerful approach for unraveling the regulatory mechanism of cholesterol metabolism. However, it is difficult to identify the mutant gene(s) due to cells are usually mutagenized chemically or physically. To identify important genes controlling cholesterol biosynthesis, an unbiased forward genetics approach named validatio...
Alternative Titles
Full title
Forward Genetic Screening for Regulators Involved in Cholesterol Synthesis Using Validation-Based Insertional Mutagenesis
Authors, Artists and Contributors
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Record Identifier
TN_cdi_plos_journals_1628247866
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1628247866
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0112632
