Dimer-Dependent Intrinsic/Basal Activity of the Class B G Protein-Coupled Receptor PAC1 Promotes Cel...
Dimer-Dependent Intrinsic/Basal Activity of the Class B G Protein-Coupled Receptor PAC1 Promotes Cellular Anti-Apoptotic Activity through Wnt/β-Catenin Pathways that Are Associated with Dimer Endocytosis
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Author / Creator
Yu, Rongjie , Cui, Zekai , Li, Mei , Yang, Yanxu and Zhong, Jiaping
Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The high expression of PACAP (pituitary adenylate cyclase-activating polypeptide)-preferring receptor PAC1 is associated with nerve injury and tumors. Our previous report (Yu R, et al. PLoS One 2012; 7: e51811) confirmed the dimerization of PAC1 and found that the M-PAC1 mutation in the N-terminal first Cys/Ala lost the ability to form dimers. In t...
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Full title
Dimer-Dependent Intrinsic/Basal Activity of the Class B G Protein-Coupled Receptor PAC1 Promotes Cellular Anti-Apoptotic Activity through Wnt/β-Catenin Pathways that Are Associated with Dimer Endocytosis
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TN_cdi_plos_journals_1628248031
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1628248031
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0113913
