Apoptotic efficacy of etomoxir in human acute myeloid leukemia cells. Cooperation with arsenic triox...
Apoptotic efficacy of etomoxir in human acute myeloid leukemia cells. Cooperation with arsenic trioxide and glycolytic inhibitors, and regulation by oxidative stress and protein kinase activities
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Fatty acid synthesis and oxidation are frequently exacerbated in leukemia cells, and may therefore represent a target for therapeutic intervention. In this work we analyzed the apoptotic and chemo-sensitizing action of the fatty acid oxidation inhibitor etomoxir in human acute myeloid leukemia cells. Etomoxir caused negligible lethality at concentr...
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Apoptotic efficacy of etomoxir in human acute myeloid leukemia cells. Cooperation with arsenic trioxide and glycolytic inhibitors, and regulation by oxidative stress and protein kinase activities
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TN_cdi_plos_journals_1636753150
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1636753150
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0115250
