Hepatic Farnesoid X-Receptor Isoforms α2 and α4 Differentially Modulate Bile Salt and Lipoprotein Me...
Hepatic Farnesoid X-Receptor Isoforms α2 and α4 Differentially Modulate Bile Salt and Lipoprotein Metabolism in Mice
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United States: Public Library of Science
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English
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United States: Public Library of Science
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The nuclear receptor FXR acts as an intracellular bile salt sensor that regulates synthesis and transport of bile salts within their enterohepatic circulation. In addition, FXR is involved in control of a variety of crucial metabolic pathways. Four FXR splice variants are known, i.e. FXRα1-4. Although these isoforms show differences in spatial and...
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Hepatic Farnesoid X-Receptor Isoforms α2 and α4 Differentially Modulate Bile Salt and Lipoprotein Metabolism in Mice
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TN_cdi_plos_journals_1636754711
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1636754711
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0115028
