Ethenoguanines Undergo Glycosylation by Nucleoside 2′-Deoxyribosyltransferases at Non-Natural Sites
Ethenoguanines Undergo Glycosylation by Nucleoside 2′-Deoxyribosyltransferases at Non-Natural Sites
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Deoxyribosyl transferases and functionally related purine nucleoside phosphorylases are used extensively for synthesis of non-natural deoxynucleosides as pharmaceuticals or standards for characterizing and quantitating DNA adducts. Hence exploring the conformational tolerance of the active sites of these enzymes is of considerable practical interes...
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Ethenoguanines Undergo Glycosylation by Nucleoside 2′-Deoxyribosyltransferases at Non-Natural Sites
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TN_cdi_plos_journals_1638004015
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1638004015
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0115082