Accumulation of Self-Reactive Naïve and Memory B Cell Reveals Sequential Defects in B Cell Tolerance...
Accumulation of Self-Reactive Naïve and Memory B Cell Reveals Sequential Defects in B Cell Tolerance Checkpoints in Sjögren’s Syndrome
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Sjögren's syndrome (SS) is an autoimmune disease characterised by breach of self-tolerance towards nuclear antigens resulting in high affinity circulating autoantibodies. Although peripheral B cell disturbances have been described in SS, with predominance of naïve and reduction of memory B cells, the stage at which errors in B cell tolerance checkp...
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Accumulation of Self-Reactive Naïve and Memory B Cell Reveals Sequential Defects in B Cell Tolerance Checkpoints in Sjögren’s Syndrome
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TN_cdi_plos_journals_1640006666
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1640006666
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0114575