ARAP3 Functions in Hematopoietic Stem Cells
ARAP3 Functions in Hematopoietic Stem Cells
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
ARAP3 is a GTPase-activating protein (GAP) that inactivates Arf6 and RhoA small GTPases. ARAP3 deficiency in mice causes a sprouting angiogenic defect resulting in embryonic lethality by E11. Mice with an ARAP3 R302,303A mutation (Arap3KI/KI) that prevents activation by phosphoinositide-3-kinase (PI3K) have a similar angiogenic phenotype, although...
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Full title
ARAP3 Functions in Hematopoietic Stem Cells
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TN_cdi_plos_journals_1640559824
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1640559824
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0116107
