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Nephrokeli, a Chinese Herbal Formula, May Improve IgA Nephropathy through Regulation of the Sphingos...

Nephrokeli, a Chinese Herbal Formula, May Improve IgA Nephropathy through Regulation of the Sphingos...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1649089361

Nephrokeli, a Chinese Herbal Formula, May Improve IgA Nephropathy through Regulation of the Sphingosine-1-Phosphate Pathway

About this item

Full title

Nephrokeli, a Chinese Herbal Formula, May Improve IgA Nephropathy through Regulation of the Sphingosine-1-Phosphate Pathway

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-01, Vol.10 (1), p.e0116873-e0116873

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Nephrokeli (NPKL) is a Chinese herbal formula that has been used to treat patients with IgA nephropathy (IgAN) for improvement of proteinuria and kidney injury. However, the mechanism remains unclear. Sphingosine-1-phosphate (S1P) and its receptors S1PR2 and S1PR3 are known to play an important role in kidney disease. Here, we tested whether NPKL i...

Alternative Titles

Full title

Nephrokeli, a Chinese Herbal Formula, May Improve IgA Nephropathy through Regulation of the Sphingosine-1-Phosphate Pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1649089361

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1649089361

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0116873

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