Nephrokeli, a Chinese Herbal Formula, May Improve IgA Nephropathy through Regulation of the Sphingos...
Nephrokeli, a Chinese Herbal Formula, May Improve IgA Nephropathy through Regulation of the Sphingosine-1-Phosphate Pathway
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United States: Public Library of Science
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English
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United States: Public Library of Science
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Nephrokeli (NPKL) is a Chinese herbal formula that has been used to treat patients with IgA nephropathy (IgAN) for improvement of proteinuria and kidney injury. However, the mechanism remains unclear. Sphingosine-1-phosphate (S1P) and its receptors S1PR2 and S1PR3 are known to play an important role in kidney disease. Here, we tested whether NPKL i...
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Nephrokeli, a Chinese Herbal Formula, May Improve IgA Nephropathy through Regulation of the Sphingosine-1-Phosphate Pathway
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TN_cdi_plos_journals_1649089361
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1649089361
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0116873