Defective Differentiation of Adipose Precursor Cells from Lipodystrophic Mice Lacking Perilipin 1
Defective Differentiation of Adipose Precursor Cells from Lipodystrophic Mice Lacking Perilipin 1
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Perilipin 1 (Plin1) localizes at the surface of lipid droplets to regulate triglyceride storage and hydrolysis in adipocytes. Plin1 defect leads to low adiposity in mice and partial lipodystrophy in human. This study investigated the roles of Plin1 in adipocyte differentiation. Plin1 null (-/-) mice showed plenty of multilocular adipocytes and smal...
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Full title
Defective Differentiation of Adipose Precursor Cells from Lipodystrophic Mice Lacking Perilipin 1
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TN_cdi_plos_journals_1656299173
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1656299173
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0117536
