Functional Comparison of Induced Pluripotent Stem Cell- and Blood-Derived GPIIbIIIa Deficient Platel...
Functional Comparison of Induced Pluripotent Stem Cell- and Blood-Derived GPIIbIIIa Deficient Platelets
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Human induced pluripotent stem cells (hiPSCs) represent a versatile tool to model genetic diseases and are a potential source for cell transfusion therapies. However, it remains elusive to which extent patient-specific hiPSC-derived cells functionally resemble their native counterparts. Here, we generated a hiPSC model of the primary platelet disea...
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Functional Comparison of Induced Pluripotent Stem Cell- and Blood-Derived GPIIbIIIa Deficient Platelets
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TN_cdi_plos_journals_1658106819
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1658106819
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0115978