Genome-Wide DNA Methylation Profiles Indicate CD8+ T Cell Hypermethylation in Multiple Sclerosis
Genome-Wide DNA Methylation Profiles Indicate CD8+ T Cell Hypermethylation in Multiple Sclerosis
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Determine whether MS-specific DNA methylation profiles can be identified in whole blood or purified immune cells from untreated MS patients.
Whole blood, CD4+ and CD8+ T cell DNA from 16 female, treatment naïve MS patients and 14 matched controls was profiled using the HumanMethylation450K BeadChip. Genotype data were used to assess genetic homo...
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Full title
Genome-Wide DNA Methylation Profiles Indicate CD8+ T Cell Hypermethylation in Multiple Sclerosis
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TN_cdi_plos_journals_1660378138
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1660378138
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0117403
