A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair
A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair
About this item
Full title
Author / Creator
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
The purpose of the present work was to progress in our understanding of the pathophysiology of L-2-hydroxyglutaric aciduria, due to a defect in L-2-hydroxyglutarate dehydrogenase, by creating and studying a mouse model of this disease. L-2-hydroxyglutarate dehydrogenase-deficient mice (l2hgdh-/-) accumulated L-2-hydroxyglutarate in tissues, most pa...
Alternative Titles
Full title
A mouse model of L-2-hydroxyglutaric aciduria, a disorder of metabolite repair
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1662632435
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1662632435
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0119540
