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Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-ar...

Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-ar...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1666309569

Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease

About this item

Full title

Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-03, Vol.10 (3), p.e0119452-e0119452

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

This study combined high resolution mass spectrometry (HRMS), advanced chemometrics and pathway enrichment analysis to analyse the blood metabolome of patients attending the memory clinic: cases of mild cognitive impairment (MCI; n = 16), cases of MCI who upon subsequent follow-up developed Alzheimer's disease (MCI_AD; n = 19), and healthy age-matc...

Alternative Titles

Full title

Untargeted metabolomic analysis of human plasma indicates differentially affected polyamine and L-arginine metabolism in mild cognitive impairment subjects converting to Alzheimer's disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1666309569

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1666309569

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0119452

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