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Histone Deacetylase Inhibition Enhances Tissue Plasminogen Activator Release Capacity in Atheroscler...

Histone Deacetylase Inhibition Enhances Tissue Plasminogen Activator Release Capacity in Atheroscler...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1666747428

Histone Deacetylase Inhibition Enhances Tissue Plasminogen Activator Release Capacity in Atherosclerotic Man

About this item

Full title

Histone Deacetylase Inhibition Enhances Tissue Plasminogen Activator Release Capacity in Atherosclerotic Man

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-03, Vol.10 (3), p.e0121196-e0121196

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

The expression of the tissue plasminogen activator (t-PA) gene appears to be under epigenetic control and can be affected by histone deacetylation inhibition. The study aimed to test if histone deacetalyase inhibitor treatment lead to increased t-PA release or reduced exhaustion in t-PA release in response to stimulation, as well as change in plasm...

Alternative Titles

Full title

Histone Deacetylase Inhibition Enhances Tissue Plasminogen Activator Release Capacity in Atherosclerotic Man

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1666747428

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1666747428

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0121196