Modulation of genetic associations with serum urate levels by body-mass-index in humans
Modulation of genetic associations with serum urate levels by body-mass-index in humans
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Huffman, Jennifer E , Albrecht, Eva , Teumer, Alexander , Mangino, Massimo , Kapur, Karen , Johnson, Toby , Kutalik, Zoltán , Pirastu, Nicola , Pistis, Giorgio , Lopez, Lorna M , Haller, Toomas , Salo, Perttu , Goel, Anuj , Li, Man , Tanaka, Toshiko , Dehghan, Abbas , Ruggiero, Daniela , Malerba, Giovanni , Smith, Albert V , Nolte, Ilja M , Portas, Laura , Phipps-Green, Amanda , Boteva, Lora , Navarro, Pau , Johansson, Asa , Hicks, Andrew A , Polasek, Ozren , Esko, Tõnu , Peden, John F , Harris, Sarah E , Murgia, Federico , Wild, Sarah H , Tenesa, Albert , Tin, Adrienne , Mihailov, Evelin , Grotevendt, Anne , Gislason, Gauti K , Coresh, Josef , D'Adamo, Pio , Ulivi, Sheila , Vollenweider, Peter , Waeber, Gerard , Campbell, Susan , Kolcic, Ivana , Fisher, Krista , Viigimaa, Margus , Metter, Jeffrey E , Masciullo, Corrado , Trabetti, Elisabetta , Bombieri, Cristina , Sorice, Rossella , Döring, Angela , Reischl, Eva , Strauch, Konstantin , Hofman, Albert , Uitterlinden, Andre G , Waldenberger, Melanie , Wichmann, H-Erich , Davies, Gail , Gow, Alan J , Dalbeth, Nicola , Stamp, Lisa , Smit, Johannes H , Kirin, Mirna , Nagaraja, Ramaiah , Nauck, Matthias , Schurmann, Claudia , Budde, Kathrin , Farrington, Susan M , Theodoratou, Evropi , Jula, Antti , Salomaa, Veikko , Sala, Cinzia , Hengstenberg, Christian , Burnier, Michel , Mägi, Reedik , Klopp, Norman , Kloiber, Stefan , Schipf, Sabine , Ripatti, Samuli , Cabras, Stefano , Soranzo, Nicole , Homuth, Georg , Nutile, Teresa , Munroe, Patricia B , Hastie, Nicholas , Campbell, Harry , Rudan, Igor , Cabrera, Claudia , Haley, Chris , Franco, Oscar H , Merriman, Tony R , Gudnason, Vilmundur , Pirastu, Mario , Penninx, Brenda W , Snieder, Harold , Metspalu, Andres , Ciullo, Marina , Pramstaller, Peter P and van Duijn, Cornelia M
Publisher
United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Scope and Contents
Contents
We tested for interactions between body mass index (BMI) and common genetic variants affecting serum urate levels, genome-wide, in up to 42569 participants. Both stratified genome-wide association (GWAS) analyses, in lean, overweight and obese individuals, and regression-type analyses in a non BMI-stratified overall sample were performed. The forme...
Alternative Titles
Full title
Modulation of genetic associations with serum urate levels by body-mass-index in humans
Authors, Artists and Contributors
Author / Creator
Albrecht, Eva
Teumer, Alexander
Mangino, Massimo
Kapur, Karen
Johnson, Toby
Kutalik, Zoltán
Pirastu, Nicola
Pistis, Giorgio
Lopez, Lorna M
Haller, Toomas
Salo, Perttu
Goel, Anuj
Li, Man
Tanaka, Toshiko
Dehghan, Abbas
Ruggiero, Daniela
Malerba, Giovanni
Smith, Albert V
Nolte, Ilja M
Portas, Laura
Phipps-Green, Amanda
Boteva, Lora
Navarro, Pau
Johansson, Asa
Hicks, Andrew A
Polasek, Ozren
Esko, Tõnu
Peden, John F
Harris, Sarah E
Murgia, Federico
Wild, Sarah H
Tenesa, Albert
Tin, Adrienne
Mihailov, Evelin
Grotevendt, Anne
Gislason, Gauti K
Coresh, Josef
D'Adamo, Pio
Ulivi, Sheila
Vollenweider, Peter
Waeber, Gerard
Campbell, Susan
Kolcic, Ivana
Fisher, Krista
Viigimaa, Margus
Metter, Jeffrey E
Masciullo, Corrado
Trabetti, Elisabetta
Bombieri, Cristina
Sorice, Rossella
Döring, Angela
Reischl, Eva
Strauch, Konstantin
Hofman, Albert
Uitterlinden, Andre G
Waldenberger, Melanie
Wichmann, H-Erich
Davies, Gail
Gow, Alan J
Dalbeth, Nicola
Stamp, Lisa
Smit, Johannes H
Kirin, Mirna
Nagaraja, Ramaiah
Nauck, Matthias
Schurmann, Claudia
Budde, Kathrin
Farrington, Susan M
Theodoratou, Evropi
Jula, Antti
Salomaa, Veikko
Sala, Cinzia
Hengstenberg, Christian
Burnier, Michel
Mägi, Reedik
Klopp, Norman
Kloiber, Stefan
Schipf, Sabine
Ripatti, Samuli
Cabras, Stefano
Soranzo, Nicole
Homuth, Georg
Nutile, Teresa
Munroe, Patricia B
Hastie, Nicholas
Campbell, Harry
Rudan, Igor
Cabrera, Claudia
Haley, Chris
Franco, Oscar H
Merriman, Tony R
Gudnason, Vilmundur
Pirastu, Mario
Penninx, Brenda W
Snieder, Harold
Metspalu, Andres
Ciullo, Marina
Pramstaller, Peter P
van Duijn, Cornelia M
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Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1667002093
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1667002093
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0119752