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Impact of the CFTR-potentiator ivacaftor on airway microbiota in cystic fibrosis patients carrying a...

Impact of the CFTR-potentiator ivacaftor on airway microbiota in cystic fibrosis patients carrying a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1671208377

Impact of the CFTR-potentiator ivacaftor on airway microbiota in cystic fibrosis patients carrying a G551D mutation

About this item

Full title

Impact of the CFTR-potentiator ivacaftor on airway microbiota in cystic fibrosis patients carrying a G551D mutation

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-04, Vol.10 (4), p.e0124124-e0124124

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Airway microbiota composition has been clearly correlated with many pulmonary diseases, and notably with cystic fibrosis (CF), an autosomal genetic disorder caused by mutation in the CF transmembrane conductance regulator (CFTR). Recently, a new molecule, ivacaftor, has been shown to re-establish the functionality of the G551D-mutated CFTR, allowin...

Alternative Titles

Full title

Impact of the CFTR-potentiator ivacaftor on airway microbiota in cystic fibrosis patients carrying a G551D mutation

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1671208377

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1671208377

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0124124

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