N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification a...
N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Ectopic calcification (EC), which is the pathological deposition of calcium and phosphate in extra-skeletal tissues, may be associated with hypercalcaemic and hyperphosphataemic disorders, or it may occur in the absence of metabolic abnormalities. In addition, EC may be inherited as part of several monogenic disorders and studies of these have prov...
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Full title
N-ethyl-N-Nitrosourea (ENU) induced mutations within the klotho gene lead to ectopic calcification and reduced lifespan in mouse models
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TN_cdi_plos_journals_1672283982
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1672283982
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0122650
