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The Chemopotential Effect of Annona muricata Leaves against Azoxymethane-Induced Colonic Aberrant Cr...

The Chemopotential Effect of Annona muricata Leaves against Azoxymethane-Induced Colonic Aberrant Cr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1672285118

The Chemopotential Effect of Annona muricata Leaves against Azoxymethane-Induced Colonic Aberrant Crypt Foci in Rats and the Apoptotic Effect of Acetogenin Annomuricin E in HT-29 Cells: A Bioassay-Guided Approach

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Full title

The Chemopotential Effect of Annona muricata Leaves against Azoxymethane-Induced Colonic Aberrant Crypt Foci in Rats and the Apoptotic Effect of Acetogenin Annomuricin E in HT-29 Cells: A Bioassay-Guided Approach

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-04, Vol.10 (4), p.e0122288-e0122288

Language

English

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Publication information

Publisher

United States: Public Library of Science

Subjects

Subjects and topics

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Scope and Contents

Contents

Annona muricata has been used in folk medicine for the treatment of cancer and tumors. This study evaluated the chemopreventive properties of an ethyl acetate extract of A. muricata leaves (EEAML) on azoxymethane-induced colonic aberrant crypt foci (ACF) in rats. Moreover, the cytotoxic compound of EEAML (Annomuricin E) was isolated, and its apopto...

Alternative Titles

Full title

The Chemopotential Effect of Annona muricata Leaves against Azoxymethane-Induced Colonic Aberrant Crypt Foci in Rats and the Apoptotic Effect of Acetogenin Annomuricin E in HT-29 Cells: A Bioassay-Guided Approach

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Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1672285118

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1672285118

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0122288

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