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Endothelial-Derived Oxidative Stress Drives Myofibroblastic Activation and Calcification of the Aort...

Endothelial-Derived Oxidative Stress Drives Myofibroblastic Activation and Calcification of the Aort...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1673119828

Endothelial-Derived Oxidative Stress Drives Myofibroblastic Activation and Calcification of the Aortic Valve

About this item

Full title

Endothelial-Derived Oxidative Stress Drives Myofibroblastic Activation and Calcification of the Aortic Valve

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-04, Vol.10 (4), p.e0123257

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

Oxidative stress is present in and contributes to calcification of the aortic valve, but the driving factors behind the initiation of valve oxidative stress are not well understood. We tested whether the valve endothelium acts as an initiator and propagator of oxidative stress in aortic valve disease.
Calcified human aortic valves showed side-sp...

Alternative Titles

Full title

Endothelial-Derived Oxidative Stress Drives Myofibroblastic Activation and Calcification of the Aortic Valve

Authors, Artists and Contributors

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1673119828

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1673119828

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0123257

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