Identification of Selective Inhibitors of the Plasmodium falciparum Hexose Transporter PfHT by Scree...
Identification of Selective Inhibitors of the Plasmodium falciparum Hexose Transporter PfHT by Screening Focused Libraries of Anti-Malarial Compounds
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United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
Development of resistance against current antimalarial drugs necessitates the search for novel drugs that interact with different targets and have distinct mechanisms of action. Malaria parasites depend upon high levels of glucose uptake followed by inefficient metabolic utilization via the glycolytic pathway, and the Plasmodium falciparum hexose t...
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Full title
Identification of Selective Inhibitors of the Plasmodium falciparum Hexose Transporter PfHT by Screening Focused Libraries of Anti-Malarial Compounds
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TN_cdi_plos_journals_1674451222
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1674451222
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0123598
