A Fast and Scalable Kymograph Alignment Algorithm for Nanochannel-Based Optical DNA Mappings
A Fast and Scalable Kymograph Alignment Algorithm for Nanochannel-Based Optical DNA Mappings
About this item
Full title
Author / Creator
Noble, Charleston , Nilsson, Adam N. , Freitag, Camilla , Beech, Jason P. , Tegenfeldt, Jonas O. , Ambjörnsson, Tobias , Naturvetenskapliga fakulteten , Strategiska forskningsområden (SFO) , Department of Physics , Strategic research areas (SRA) , Faculty of Science , Lunds universitet , Profilområden och andra starka forskningsmiljöer , Lund University , Solid State Physics , NanoLund: Centre for Nanoscience , Atomic Physics , Profile areas and other strong research environments , Atomfysik , Fysiska institutionen and Fasta tillståndets fysik
Publisher
United States: Public Library of Science
Journal title
Language
English
Formats
Publication information
Publisher
United States: Public Library of Science
Subjects
More information
Scope and Contents
Contents
Optical mapping by direct visualization of individual DNA molecules, stretched in nanochannels with sequence-specific fluorescent labeling, represents a promising tool for disease diagnostics and genomics. An important challenge for this technique is thermal motion of the DNA as it undergoes imaging; this blurs fluorescent patterns along the DNA an...
Alternative Titles
Full title
A Fast and Scalable Kymograph Alignment Algorithm for Nanochannel-Based Optical DNA Mappings
Authors, Artists and Contributors
Author / Creator
Nilsson, Adam N.
Freitag, Camilla
Beech, Jason P.
Tegenfeldt, Jonas O.
Ambjörnsson, Tobias
Naturvetenskapliga fakulteten
Strategiska forskningsområden (SFO)
Department of Physics
Strategic research areas (SRA)
Faculty of Science
Lunds universitet
Profilområden och andra starka forskningsmiljöer
Lund University
Solid State Physics
NanoLund: Centre for Nanoscience
Atomic Physics
Profile areas and other strong research environments
Atomfysik
Fysiska institutionen
Fasta tillståndets fysik
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_plos_journals_1674475223
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1674475223
Other Identifiers
ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0121905
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