A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with...
A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Lung adenocarcinoma, the most common subtype of lung cancer, is the leading cause of cancer death worldwide. Despite attempts for the treatment of lung cancer which have been accumulating, promising new therapies are still needed. Here, we found that cyclic-AMP response element-binding protein (CREB)-CREB binding protein (CBP) transcription factors...
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Full title
A Novel Small-Molecule Inhibitor Targeting CREB-CBP Complex Possesses Anti-Cancer Effects along with Cell Cycle Regulation, Autophagy Suppression and Endoplasmic Reticulum Stress
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TN_cdi_plos_journals_1674683304
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1674683304
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0122628
