The Effect of Protease Inhibitors on the Induction of Osteoarthritis-Related Biomarkers in Bovine Fu...
The Effect of Protease Inhibitors on the Induction of Osteoarthritis-Related Biomarkers in Bovine Full-Depth Cartilage Explants
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Publisher
United States: Public Library of Science
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Language
English
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United States: Public Library of Science
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Contents
The specific degradation of type II collagen and aggrecan by matrix metalloproteinase (MMP)-9, -13 and ADAMTS-4 and -5 (aggrecanase-1 and -2) in the cartilage matrix is a critical step in pathology of osteoarthritis (OA). The aims of this study were: i) To investigate the relative contribution of ADAMTS-4 and ADAMTS-5 to cartilage degradation upon...
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Full title
The Effect of Protease Inhibitors on the Induction of Osteoarthritis-Related Biomarkers in Bovine Full-Depth Cartilage Explants
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TN_cdi_plos_journals_1676150253
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1676150253
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0122700
