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TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children

TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1676151937

TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children

About this item

Full title

TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children

Publisher

United States: Public Library of Science

Journal title

PloS one, 2015-04, Vol.10 (4), p.e0123244-e0123244

Language

English

Formats

Publication information

Publisher

United States: Public Library of Science

More information

Scope and Contents

Contents

TNF-α and IFN-γ play a role in the development of mucosal damage in celiac disease (CD). Polymorphisms of TNFA and IFNG genes, as well as of the TNFRSF1A gene, encoding the TNF-α receptor 1, might underlie different inter-individual disease susceptibility over a common HLA risk background. The aims of this study were to ascertain whether five SNPs...

Alternative Titles

Full title

TNFA Haplotype Genetic Testing Improves HLA in Estimating the Risk of Celiac Disease in Children

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_plos_journals_1676151937

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1676151937

Other Identifiers

ISSN

1932-6203

E-ISSN

1932-6203

DOI

10.1371/journal.pone.0123244

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