Activating the Wnt/β-Catenin Pathway for the Treatment of Melanoma – Application of LY2090314, a Nov...
Activating the Wnt/β-Catenin Pathway for the Treatment of Melanoma – Application of LY2090314, a Novel Selective Inhibitor of Glycogen Synthase Kinase-3
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United States: Public Library of Science
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English
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United States: Public Library of Science
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It has previously been observed that a loss of β-catenin expression occurs with melanoma progression and that nuclear β-catenin levels are inversely proportional to cellular proliferation, suggesting that activation of the Wnt/β-catenin pathway may provide benefit for melanoma patients. In order to further probe this concept we tested LY2090314, a...
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Activating the Wnt/β-Catenin Pathway for the Treatment of Melanoma – Application of LY2090314, a Novel Selective Inhibitor of Glycogen Synthase Kinase-3
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TN_cdi_plos_journals_1676151954
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1676151954
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0125028
