ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-...
ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis
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United States: Public Library of Science
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Language
English
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Publisher
United States: Public Library of Science
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Contents
Airways infection with Mycobacterium tuberculosis (Mtb) is contained mostly by T cell responses, however, Mtb has developed evasion mechanisms which affect antigen presenting cell (APC) maturation/recruitment delaying the onset of Ag-specific T cell responses. Hypothetically, bypassing the natural infection routes by delivering antigens directly to...
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Full title
ESAT-6 Targeting to DEC205+ Antigen Presenting Cells Induces Specific-T Cell Responses against ESAT-6 and Reduces Pulmonary Infection with Virulent Mycobacterium tuberculosis
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TN_cdi_plos_journals_1676151965
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_plos_journals_1676151965
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ISSN
1932-6203
E-ISSN
1932-6203
DOI
10.1371/journal.pone.0124828
